Johnson & Johnson navigates the loss of exclusivity for its blockbuster immunology drug, Stelara.

Stelara sales declined by $913 million in the second quarter of 2026. Newer growth products generated $2.43 billion in revenue. This revenue more than offset the Stelara decline.

Immunology treatment Tremfya and oncology drugs Darzalex and Carvykti drove this performance.

J&J's Innovative Medicine division grew despite the Stelara headwind.

The company raised its full-year 2026 sales guidance. It projects revenues to approach or exceed $101 billion.

Analysts note weaker growth in the MedTech division.