Painreform is trading 21.29% up at $1.25, with no clear, reliable company-specific catalyst identified for the pre-market move.

  • It closed at $1.03 on August 12, 2026.
  • Available coverage shows no verified August 13 announcement, earnings release, or regulatory event; broader markets are only modestly higher and do not explain the sharp gain.
  • The move may reflect low-liquidity speculative trading; CNN’s listing reports no recent press releases available.